The 19th European Symposium on Organic Reactivity (ESOR2023) was held from 19 to 22 September in Amsterdam, The Netherlands.
SCOPE
The primary objective of ESOR2023 is the exchange of the latest developments and ideas in the field of physical and theoretical organic chemistry.
The ESOR series is a string of biennial events that are hosted in different European cities. The conference series started in Paris in 1987 and it has been held every second year ever since: in Padova, Italy (1989), Göteborg, Sweden (1991), Newcastle, UK (1993), Santiago de Compostela, Spain (1995), Louvain la Neuve, Belgium (1997), Ulm, Germany (1999), Cavtat (Dubrovnik), Croatia (2001), Oslo, Norway (2003), Rome, Italy (2005), Faro, Portugal (2007), Haifa, Israel, (2009), Tartu, Estonia (2011), Prague, Czech Republic (2013), Kiel, Germany (2015), Durham, UK (2017), and Dubrovnik, Croatia (2019). For more information about the history of ESOR, click here.
PROGRAM
–––– Tuesday 19 September ––––
08:30 – 09:30 | Registration + coffee and tea
09:30 – 09:40 | Opening by F. Matthias Bickelhaupt and Rainer Herges
09:40 – 10:30 | Ben Feringa | In Control with Light
10:30 – 11:00 | Thomas Hansen | Exploring Chemical Glycosylation Reactions: Can We Control Them?
11:00 – 11:40 | Coffee break
11:40 – 12:10 | Darren Dixon | Catalyst Control in Complex Natural Product Synthesis
12:10 – 12:25 | Robert J. Mayer | A Mechanistic Approach to Nonenzymatic Reduction Reactions: When Metals Take the Role of Enzymes
12:25 – 12:40 | Ganna Gryn’ova | Ab initio and Machine Learning Chemistry of Radical Ions
12:40 – 12:55 | Martin Breugst | Scope and Limitations of Iodine Catalysis
12:55 – 14:10 | Lunch
14:10 – 14:40 | Israel Fernández | The Pauli Repulsion Lowering Concept in Catalysis
14:40 – 14:55 | Jason B. Harper | Efficient Measurements of Nucleophilicities
14:55 – 15:10 | Kirill Nikitin | In the CORE of Olefination: an Umpolung / Eigenbase Update
15:10 – 15:25 | Marc-Etienne Moret | Activation of E–H bonds (E=O, S, N) at Bicyclic Silanides
15:25 – 16:00 | Coffee break
16:00 – 16:40 | Rainer Herges | Early Detection of Cancer by Metabolic Imaging
16:40 – 17:10 | Anja Palmans | Folding Single Polymer Chains into Functional Materials
17:10 – 17:25 | Pascal Vermeeren | Revising the Rationale Behind C–H Bond Distances
17:25 – 17:45 | Conference photo
17:45 – 20:00 | Poster session and walking dinner
–––– Wednesday 20 September ––––
09:00 – 09:40 | Franziska Schoenebeck | Accelerating Advances in Catalysis – Concepts, Insights, Strategies
09:40 – 09:55 | Armin R. Ofial | A Tour to the Upper Limit of Nucleophilicity Scales: Mesoionic N-Heterocyclic Olefins
09:55 – 10:10 | Jordi Poater | Through-space Stabilization of an Imidazolium Cation by Aromatic Rings
10:10 – 10:40 | Thibault Cantat | En Route to More Energy Efficient Silicon Hydrides Using Molecular Catalysis
10:40 – 11:20 | Coffee break
11:20 – 11:50 | Guillaume Berionni | Geometrically Constrained Lewis Acids and Bases for Frustrated Lewis Pair Chemistry
11:50 – 12:05 | Itzhak Bilkis | Oxoammonium Salts as Mediators in Water Oxidation
12:05 – 12:20 | E. Daiann Sosa Carrizo | Understanding the Unexpected Selectivity in the Rh(II) Catalyzed C(sp3)-H Amination of Propylbenzene
12:20 – 12:50 | Henry Dube | Indigoid Molecular Switches and Machines
12:50 – 14:00 | Lunch
14:00 – 14:30 | Frank de Proft | Influence of Mechanical Force and External Pressure on Chemical Reactivity
14:30 – 14:45 | Lucas de Azevedo Santos | Intermolecular Covalent Interactions
14:45 – 15:00 | Andreea Gheorghe | Chemistry Europe
15:00 – 15:30 | Han Zuilhof | Intrinsically Chiral and Multimodal Click Chemistry
15:30 – 16:00 | Coffee break
16:00 – 16:30 | Hrvoj Vančik | Reactions in Crystals and Limits of the Concept of Reaction Mechanism
16:30 – 16:45 | Victor Chechik | Probing the Mechanism of Trialkylborane-Oxygen Radical Initiators by Trapping Radical Intermediates
16:45 – 17:25 | Einar Uggerud | The Factors Determining Reactivity in Nucleophilic Substitution
18:15 – 20:30 | International Board Meeting
–––– Thursday 21 September ––––
09:00 – 09:40 | Sijbren Otto | Mechanisms of Emergence in the Approach Toward De-Novo Life
09:40 – 09:55 | Harvey J. A. Dale | Kinetics and Mechanism of Azole n-π* Catalysed Acylation
09:55 – 10:10 | Mansour Nawasreh | Methoxylation/Demethoxylation Toward anti-Cancer Cephalostatins
10:10 – 10:40 | Sami Lakhdar | New Polar and Radical Methods for the Formation of Carbon-Phosphorus Bonds: A Mechanistically-Driven Approach
10:40 – 11:20 | Coffee break
11:20 – 11:35 | Davor Šakić | Regioselectivity in the Hofmann–Löffler–Freytag Reaction: A Computational Analysis of Rearrangement Reactions
11:35 – 11:50 | Susanna Wood | Mechanistic Studies of Benzylic Oxidation Using Chlorine Dioxide
11:50 – 12:05 | Nikolaos Vagkidis | Substituted Phenylhydroxycarbenes in the Carbonyl-ene Reaction in Solution
12:05 – 12:20 | Maria de Lurdes dos Santos Cristiano | Insights on the Structure and Photochemistry of Synthetic Compounds Bearing the Endoperoxide Pharmacophore
12:20 – 12:35 | Ken Yamazaki | Rationalization of Chemical Selectivity in Catalytic Reactions
12:35 – 13:45 | Lunch
13:45 – 14:15 | Renana Gershoni-Poranne | A Journey to the Land of Polycyclic Aromatic Systems
14:15 – 14:30 | Moisés Canle López | A Multi-site Adsorption Model for Heterogeneous Photocatalysis
14:30 – 14:45 | Ian W. Ashworth | Nitrosamine Formation in Pharmaceuticals: Developing Biased Kinetic Models to Assess Nitrosation Risk in Solid Drug Products
14:45 – 15:15 | Marcin Stępień | π-Conjugated Oligoradicaloids and Anions: Aromaticity, Magnetism, and Non-covalent Interactions
15:15 – 15:50 | Coffee break
15:50 – 16:30 | Fernando Cossío | Concerted and Stepwise Cycloadditions: Applications to Medicinal Chemistry and Particle Physics
16:30 – 16:45 | Celine Nieuwland | How the Chalcogen Atom Size Dictates the Hydrogen-Bonding Capability of Amides
18:30 – 20:30 | Dinner cruise
–––– Friday 22 September ––––
09:00 – 09:40 | Paolo Melchiorre | Photochemistry & Organocatalysis: New Radical Opportunities
09:40 – 09:55 | Ian H. Williams | Fundamentalist vs. Canonical Descriptions of Isotope Effects in Enzymic Reactivity
09:55 – 10:10 | Jonny Proppe | Uncertainty Quantification of Organic Reactivity
10:10 – 10:40 | Ralph Tonner-Zech | Surface-Mediated Organic Reactivity: Chemistry on and with the Surface
10:40 – 11:20 | Coffee break
11:20 – 12:00 | AnnMarie O’Donoghue | Mechanistic Evaluation of Bis-aminocyclopropenylidenes as Nucleophilic Organocatalysts
12:00 – 12:15 | Boris Maryasin | Enhancing Organic Chemistry With Calculations: From Density Functional Theory to Machine Learning
12:15 – 12:30 | Piotr de Silva | Computational framework for automated discovery of degradation reaction mechanisms of organic redox flow battery materials
12:30 – 13:00 | Leonard Prins | Controlling Chemical Reactivity in Time and Space
13:00 – 13:10 | Poster prize by Trevor A. Hamlin
13:10 – 13:15 | Closing by F. Matthias Bickelhaupt and Leonard Prins
13:15 – 14:15 | Lunch
* Keynote | Invited | Contributed
ORGANIZING COMMITTEE
Matthias Bickelhaupt – co-chair
Chris Slootweg – co-chair
Célia Fonseca Guerra – co-chair
Brigitte Horsten-Niehe – conference secretary
INTERNATIONAL STANDING COMMITTEE OF ESOR CONFERENCES
Rainer Herges (Kiel, Germany) – Chairman
Hrvoj Vančik (Zagreb, Croatia)
Hans-Ullrich Siehl (Ulm, Germany)
Moisés Canle López (A Coruña, Spain)
AnnMarie O'Donoghue (Durham, United Kingdom)
Koop Lammertsma (Amsterdam, The Netherlands)
Amnon Stanger (Haifa, Israel)
Maria de Lurdes dos Santos Cristiano (Faro, Portugal)
Einar Uggerud (Oslo, Norway)
Matthias Bickelhaupt (Amsterdam, The Netherlands)
Leonard Prins (Padova, Italy)